Background：Vasorin (VASN),a single-pass type I membrane protein, is also known as protein slit-like 2 and SLITL2, which contains one EGF-like domain, ten LRR (leucine-rich) repeats, one LRRCT domain and one LRRNT domain.
VASN is expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle.
VASN can interact selectively and non-covalently with TGF-beta, transform growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types.
In general, VASN may act as an inhibitor of TGF-beta signaling.
仕様
サイズ：100ug
Source：Human Vasorin, His Tag (VAN-H52H3) is expressed from human 293 cells (HEK293). It contains AA Cys 24 - Pro 575 (Accession # AAH68575).
Molecule：Vasorin
Synonyms：VASN,SLITL2,Vasorin
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Cys 24 - Pro 575
Conjugate：Unconjugated
Accession：AAH68575
Molecular Weight：61.6 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 61.6 kDa. The protein migrates as 80-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
