86-7911-73 ［取扱停止］Human Stathmin 1 / STMN1 Protein, His Tag 1mg ST1-H5149
特徴
- Background：Stathmin (STMN1), a member of the stathmin family, is also known as Leukemia-associated phosphoprotein p18, Oncoprotein 18 (Op18), Phosphoprotein p19 (pp19), Protein Pr22 and pp17, which contains one SLD (stathmin-like) domain.
- The function of STMN1 as an important regulatory protein of microtubule dynamics has been well-characterized.
- Stathmin (STMN1) interacts with two molecules of dimeric α,β-tubulin to form a tight ternary complex called the T2S complex.One mole of STMN1 binds to two moles of tubulin dimers through the stathmin-like domain (SLD).When STMN1 sequesters tubulin into the T2S complex, tubulin becomes non-polymerizable.
- Without tubulin polymerization, there is no microtubule assembly.STMN1 also promotes microtubule disassembly by acting directly on the microtubule ends.
仕様
- サイズ：1mg
- Source：Human Stathmin 1, His Tag (ST1-H5149) is expressed from E.coli cells. It contains AA Ala 2 - Asp 149 (Accession # NP_981946).
- Molecule：Stathmin 1
- Synonyms：STMN1,Stathmin,C1orf215,LAP18,OP18
- Species：Human
- Tag：His Tag
- Expression Systems：E.coli
- Expression Rigeion：Ala 2 - Asp 149
- Conjugate：Unconjugated
- Accession：NP_981946
- Molecular Weight：18.1 kDa
- Characteristics：This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 18.1 kDa. The protein migrates as 18 kDa under reducing (R) condition (SDS-PAGE).
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>95% as determined by SDS-PAGE.
- Buffer：PBS, pH7.4
- Package Size：1mg*1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-7911-74
Human Stathmin 1 / STMN1 Protein, His Tag 100ug
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86-7911-73
Human Stathmin 1 / STMN1 Protein, His Tag 1mg
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