Background：SLAM family member 7 (SLAMF7) is also known as CD2-like receptor-activating cytotoxic cells (CRACC), Membrane protein FOAP-12, CD antigen CD319, Novel Ly9, Protein 19A, which is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors.
SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea.
Isoform 1 of SLAMF7 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway.
May play a role in lymphocyte adhesion.
Isoform 3 of SLAMF7 does not mediate any NK cell activation.
仕様
サイズ：100ug
Source：Human SLAMF7, Fc Tag (SL7-H5256) is expressed from human 293 cells (HEK293). It contains AA Ser 23 - Met 226 (Accession # AAH27867).
Molecule：SLAMF7
Synonyms：SLAMF7,CD319,CS1,CRACC,19A,FOAP-12
Species：Human
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion：Ser 23 - Met 226
Conjugate：Unconjugated
Accession：AAH27867
Molecular Weight：49.0 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 49.0 kDa. The protein migrates as 60-67 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
