86-7911-32 ［取扱停止］Human PSME3 / PA28g Protein, His Tag 100ug PS3-H5142
特徴
- Background：Proteasome activator complex subunit 3 (PSME3),a member of the PA28 family, is also known as 11S regulator complex subunit gamma (REG-gamma), activator of multicatalytic protease subunit 3 and proteasome activator 28 subunit gamma (PA28gamma).
- PSME3 activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits.
- PSME3 can also facilitate the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage.
- Furthermore,PSME3 may also be involved in cell cycle regulation.
仕様
- サイズ：100ug
- Source：Human PSME3, His Tag (PS3-H5142) is expressed from E.coli cells. It contains AA Ala 2 - Tyr 254 (Accession # P61289-1).
- Molecule：PSME3
- Synonyms：PSME3,PA28gamma,REG-gamma
- Species：Human
- Tag：His Tag
- Expression Systems：E.coli
- Expression Rigeion：Ala 2 - Tyr 254
- Conjugate：Unconjugated
- Accession：NP_005780.2
- Molecular Weight：30.3 kDa
- Characteristics：This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 30.3 kDa. The protein migrates as 28-33 kDa under reducing (R) condition (SDS-PAGE).
- Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
- Purity：>95% as determined by SDS-PAGE.
- Buffer：50 mM Tris, 150 mM NaCl, pH7.5
- Package Size：100ug*1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-7911-31
Human PSME3 / PA28g Protein, His Tag 1mg
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86-7911-32
Human PSME3 / PA28g Protein, His Tag 100ug
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