Background：Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family.
NCR1 contains two Ig-like (immunoglobulin-like) domains.
NCR1 interacts with CD247 and FCER1G.
NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
仕様
サイズ：50ug
Source：Human NKp46, Fc Tag (NC1-H5257) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Asn 254 (Accession # AAH64806).
Molecule：NKp46
Synonyms：NCR1,LY94,CD335,NK-p46,hNKp46
Species：Human
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion：Gln 22 - Asn 254
Conjugate：Unconjugated
Accession：AAH64806
Molecular Weight：53.0 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 53.0 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
Purity：>95% as determined by SDS-PAGE.
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
