Background：MHC class I polypeptide-related sequence A (MICA) belongs to the MHC class I family and MIC subfamily.
MICA contains one Ig-like C1-type (immunoglobulin-like) domain.
Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta-2-microglobulin.
MICA acts as a stress-induced self-antigen that is recognized by gamma delta T-cells.
MICA is ligand for the KLRK1/NKG2D receptor.
MICA bind to KLRK1 leads to cell lysis.
仕様
サイズ：100ug
Source：Human MICA, His Tag (MIA-H5221) is expressed from human 293 cells (HEK293). It contains AA Glu 24 - Gln 308 (Accession # AAH16929.1).
Molecule：MICA
Synonyms：MIC-A
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Glu 24 - Gln 308
Conjugate：Unconjugated
Accession：AAH16929.1
Molecular Weight：33.8 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 33.8 kDa. The protein migrates as 45-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
