Background：Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family.
Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin.
Both MPF and the cleaved form of mesothelin are N-glycosylated.
Mesothelin / MSLN can interacts with MUC16.
The membrane-anchored forms of MSLN may play a role in cellular adhesion.
MPF potentiates megakaryocyte colony formation in vitro.
仕様
サイズ：100ug
Source：Human Mesothelin (37-286), His Tag (MSN-H5222) is expressed from human 293 cells (HEK293). It contains AA Leu 37 - Arg 286 (Accession # AAH09272).
Molecule：Mesothelin
Synonyms：MSLN,Mesothelin,MPF
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Leu 37 - Arg 286
Conjugate：Unconjugated
Accession：AAH09272
Molecular Weight：27.5 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27.5 kDa. The protein migrates as 32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
