Background：Ly6/PLAUR domain-containing protein 3 (LYPD3) is also known as MIG-C4 ,C4.4A, GPI-anchored metastasis-associated protein C4.4A homolog and Matrigel-induced gene C4 protein,which is a cell membrane protein containing two UPAR/Ly6 domains.
LYPD3 is expressed in placenta, skin and urothelium.
LYPD3 is found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues.
LYPD3 play a role in supporting cell migration and it is not only probably involved in urothelial cell-matrix interactions, but also in tumor progression.
仕様
サイズ：100ug
Source：Human LYPD3, His Tag (LY3-H52H5) is expressed from human 293 cells (HEK293). It contains AA Leu 31 - His 286 (Accession # AAH39167).
Molecule：LYPD3
Synonyms：LYPD3,MIG-C4,C4.4A
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Leu 31 - His 286
Conjugate：Unconjugated
Accession：AAH39167
Molecular Weight：28.7 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.7 kDa. The protein migrates as 45-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
