Background：Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2) is also known as CD85 antigen-like family member D (CD85d), Immunoglobulin-like transcript 4 (ILT-4), Monocyte / macrophage immunoglobulin-like receptor 10 (MIR-10), which is a member of the the subfamily B class of LIR receptors.
LILRB2 is receptor for class I MHC antigens.
LILRB2 recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles.
LILRB2 competes with CD8A for binding to class I MHC antigens.
LILRB2 / CD85d inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
仕様
サイズ：100ug
Source：Human LILRB2, His Tag (LI2-H5220) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Val 461 (Accession # AAH36827).
Molecule：LILRB2
Synonyms：LILRB2,ILT4,LIR2,MIR10,CD85d
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Gln 22 - Val 461
Conjugate：Unconjugated
Accession：AAH36827
Molecular Weight：48.6 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 48.6 kDa. The protein migrates as 58-67 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
