Background:Lipopolysaccharide-binding protein (LBP),a member of the BPI/LBP/Plunc superfamily, BPI/LBP family, is detected in blood serum.
LBP plays a role in the innate immune response.
Alao,LBP can bind to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and act as an affinity enhancer for CD14, facilitating its association with LPS.
Furthermore, LBP is able to promote the release of cytokines in response to bacterial lipopolysaccharide.
仕様
サイズ:100ug
Source:Human Lipopolysaccharide, His Tag (LBP-H52H5) is expressed from human 293 cells (HEK293). It contains AA Ala 26 - Val 481 (Accession # P18428-1 (I465F)).
Molecule:Lipopolysaccharide-binding protein / LBP
Synonyms:Lipopolysaccharide-binding protein,LBP
Species:Human
Tag:His Tag
Expression Systems:HEK293
Expression Rigeion:Ala 26 - Val 481
Conjugate:Unconjugated
Accession:NP_004130.2 (I465F)
Molecular Weight:52.8 kDa
Characteristics:This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 52.8 kDa. The protein migrates as 62 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.