Background：Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains.
The LAG3 gene contains 8 exons.
The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4.
LAG3 /CD223 involved in lymphocyte activation.
LAG3 /CD223 binds to HLA class-II antigens.
仕様
サイズ：100ug
Source：Human LAG-3, His Tag (LA3-H5222) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Leu 450 (Accession # P18627-1).
Molecule：LAG-3
Synonyms：LAG3,CD223,FDC
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Leu 23 - Leu 450
Conjugate：Unconjugated
Accession：NP_002277.4
Molecular Weight：47.1 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus, and has a calculated MW of 47.1 kDa. The predicted N-terminus is Leu 23. The reducing (R) protein migrates as 55-60 kDa in SDS-PAGE due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
