Background:Heat shock protein HSP 90-alpha (HSP90AA1 or HSP90A) is also known as Heat shock 86 kDa (HSP 86 or HSP86), Renal carcinoma antigen NY-REN-38, HSPC1, HSPCA, EL52, HSP89A, HSP90N, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2, which belongs to the heat shock protein 90 family.
HSP90AA1 undergoes a functional cycle that is linked to its ATPase activity.
This cycle probably induces conformational changes in the client proteins, thereby causing their activation.
HSP90AA1 interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
仕様
サイズ:100ug
Source:Human HSP90AA1, GST Tag (HS1-H513x) is expressed from E.coli cells. It contains AA Glu 535 - Asp 732 (Accession # NP_005339).
Characteristics:This protein carries a GST tag at the N-terminus. The protein has a calculated MW of 49.3 kDa. The protein migrates as 49 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.