Background：Galectin-9 (LGALS9) is also known as tumor antigen HOM-HD-21 and ecalectin.
Galectins are a family of proteins defined by their binding specificity for β-galactoside sugars, such as N-acetyllactosamine (Galβ1-3GlcNAc or Galβ1-4GlcNAc), which can be bound to proteins by either N-linked or O-linked glycosylation.
As for Galectin-9, it has high affinity for the Forssman pentasaccharide, and it is also the ligand for HAVCR2/TIM3.
Forthermore, Galectin-9 stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth.
仕様
サイズ：50ug
Source：Human Galectin-9, His Tag (LG9-H5244) is expressed from human 293 cells (HEK293). It contains AA Ala 2 - Thr 323 (Accession # O00182-2).
Molecule：Galectin-9
Synonyms：Galectin-9,LGALS9,Ecalectin
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Ala 2 - Thr 323
Conjugate：Unconjugated
Accession：BAA31542.1
Molecular Weight：36.6 kDa
Characteristics：This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 36.6 kDa. The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
Purity：>95% as determined by SDS-PAGE.
Buffer：20 mM MOPS, 50 mM NaCl, 1 mM EDTA, 2 mM DTT, pH7.4
