Background：Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) is also known as immunophilin FKBP52.
FKBP4 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking.
FKBP4 has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506.
FKBP4 interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes.
仕様
サイズ：50ug
Source：Human FKBP4, His,PA Tag (FK4-H52Q3) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 459 (Accession # AAH01786).
Molecule：FKBP4
Synonyms：FKBP4,FKBP52
Species：Human
Tag：His Tag & PA Tag
Expression Systems：HEK293
Expression Rigeion：Met 1 - Ala 459
Conjugate：Unconjugated
Accession：AAH01786
Molecular Weight：55.1 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus, followed by a PA tag, and has a calculated MW of 55.1 kDa. The reducing (R) protein migrates as 60 kDa in SDS-PAGE.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
