Background:Ciliary neurotrophic factor receptor subunit alpha (CNTFR or CNTFR-alpha) belongs to the type I cytokine receptor family and type 3 subfamily.
CNTFR contains two fibronectin type-III domains and one Ig-like C2-type (immunoglobulin-like) domain.
This receptor and its cognate ligand support the survival of neurons.
This receptor is most closely related to the interleukin-6 receptor.
This receptor possesses an unusual attachment to the cell membrane through a glycophosphatidylinositol linkage.
仕様
サイズ:100ug
Source:Human CNTF R alpha, His Tag (CNR-H5225) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Pro 346 (Accession # AAH01492).
Molecule:CNTF R alpha
Synonyms:CNTFR,CNTF R alpha
Species:Human
Tag:His Tag
Expression Systems:HEK293
Expression Rigeion:Gln 23 - Pro 346
Conjugate:Unconjugated
Accession:AAH01492
Molecular Weight:37.6 kDa
Characteristics:This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.6 kDa. The protein migrates as 45-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.