Background:Leukocyte differentiation antigen CD84 is also known as SLAM family member 5 (SLAMF5), which belongs to immunoglobulin (Ig) superfamily.
CD84 / SLAMF5 contains one Ig-like C2-type (immunoglobulin-like) domain.
CD84 plays a role as adhesion receptor functioning by homophilic interactions and by clustering.
CD84 / SLAMF5 increases proliferative responses of activated T-cells and SH2D1A/SAP does not seen be required for this process.
Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A/SAP-dependent pathway.
仕様
サイズ:100ug
Source:Human CD84, His Tag (CD4-H5229) is expressed from human 293 cells (HEK293). It contains AA Lys 22 - Gly 225 (Accession # AAH20063).
Molecule:CD84
Synonyms:CD84,SLAMF5,LY9B,SLAMF5
Species:Human
Tag:His Tag
Expression Systems:HEK293
Expression Rigeion:Lys 22 - Gly 225
Conjugate:Unconjugated
Accession:AAH20063
Molecular Weight:23.6 kDa
Characteristics:This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 23.6 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.