Background：CD200 is also known as OX-2 membrane glycoprotein (OX-2), is a type-1 membrane glycoprotein, which contains two immunoglobulin domains (1 Ig-like C2-type (immunoglobulin-like) domain and Ig-like V-type (immunoglobulin-like) domain), and thus belongs to the immunoglobulin superfamily.
CD200 / OX-2 is widely expressed in multiple cell types.
CD200 interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function.
OX-2 / CD200 and CD200R associate via their respective N-terminal Ig-like domains.
CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.
仕様
サイズ：100ug
Source：Human CD200, His Tag (OX2-H5228) is expressed from human 293 cells (HEK293). It contains AA Gln 31 - Gly 232 (Accession # AAH22522).
Molecule：CD200
Synonyms：CD200,MOX1,MOX2,MRC,OX-2,My033
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Gln 31 - Gly 232
Conjugate：Unconjugated
Accession：AAH22522
Molecular Weight：23.3 kDa
Characteristics：This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 23.3 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
