Background：Butyrophilin subfamily 1 member A1 (BTN1A1) is also known as BTN, which is a member of the immunoglobulin superfamily and the major protein associated with fat droplets in the milk.
BTN1A1 may have a cell surface receptor function.
The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families.
Furthermore, BTN1A1 regulates the amount of lipids and size of droplets expressed in milk and inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
仕様
サイズ：100ug
Source：Human BTN1A1, Fc Tag (BT1-H5253) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Arg 242 (Accession # AAH96312).
Molecule：BTN1A1
Synonyms：BTN1A1,Butyrophilin,BTN
Species：Human
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion：Ala 27 - Arg 242
Conjugate：Unconjugated
Accession：AAH96312
Molecular Weight：50.6 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.6 kDa. As a result of glycosylation, the protein migrates as 55-66 kDa under reducing (R) condition, and 116-130 kDa under non-reducing (NR) condition (SDS-PAGE).
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
Purity：>95% as determined by SDS-PAGE.
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
