Background:B- and T-lymphocyte attenuator (BTLA) is also known as B- and T-lymphocyte-associated protein, CD antigen CD272.
BTLA contains one Ig-like V-type (immunoglobulin-like) domain.
As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response.
BTLA / CD272 can interact with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, and interact with TNFRSF14/HVEM.
仕様
サイズ:100ug
Source:Human BTLA, Fc Tag (BTA-H5255) is expressed from human 293 cells (HEK293). It contains AA Lys 31 - Thr 134 (Accession # NP_001078826.1).
Molecule:BTLA
Synonyms:BTLA,CD272
Species:Human
Tag:Fc Tag
Expression Systems:HEK293
Expression Rigeion:Lys 31 - Thr 134
Conjugate:Unconjugated
Accession:NP_001078826.1
Molecular Weight:38.7 kDa
Characteristics:This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 38.7 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level:Less than 1.0 EU per ug by the LAL method.
Purity:>92% as determined by SDS-PAGE.
Buffer:Tris with Glycine, Arginine and NaCl, pH7.5