Background：Angiopoietin-related protein 4 (ANGPTL4) is also known as Hepatic fibrinogen / angiopoietin - related protein (HFARP), ARP4, PGAR.
ANGPTL4 contains one fibrinogen C-terminal domain.
ANGPTL4 is a homooligomer , and the homooligomer undergoes proteolytic processing to release its carboxyl fibrinogen-like domain, which circulates as a monomer.
The homooligomer unprocessed form is able to interact with the extracellular matrix.
ANGPTL4 may act as a regulator of angiogenesis and modulate tumorigenesis.
ANGPTL4 inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage.
ANGPTL4 may exert a protective function on endothelial cells through an endocrine action.
仕様
サイズ：100ug
Source：Human Angiopoietin-like 4 (166-406), His Tag (AN4-H5243) is expressed from human 293 cells (HEK293). It contains AA Pro 166 - Ser 406 (Accession # Q9BY76-1).
Molecule：Angiopoietin-like 4
Synonyms：ANGPTL4,ANGPTL2,ARP4,FIAF,HFARP,NL2,PGAR,pp1158,Angiopoietin like 4
Species：Human
Tag：His Tag
Expression Systems：HEK293
Expression Rigeion：Pro 166 - Ser 406
Conjugate：Unconjugated
Accession：NP_647475.1
Molecular Weight：27.9 kDa
Characteristics：This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 27.9 kDa. The protein migrates as 31-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
