Background：Tumor necrosis factor receptor superfamily member 25 (TNFRSF25) is also known as Apo-3, Death receptor 3 (DDR3 or DR3), Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor TRAMP, Lymphocyte-associated receptor of death, Apo-3, which is a member of the TNF-receptor superfamily.
TNFRSF25 is a homodimer protein, which can Interact strongly via the death domains with TNFRSF1 and TRADD to activate at least two distinct signaling cascades, apoptosis and NF-kappa-B signaling.
TNFRSF25 is receptor for TNFSF12 / APO3L / TWEAK.
仕様
サイズ：100ug
Source：Cynomolgus DR3, Fc Tag (TN5-C5257) is expressed from human 293 cells (HEK293). It contains AA Gln 20 - Gly 203 (Accession # G7NTB5-1).
Molecule：DR3 / TNFRSF25
Synonyms：TNFRSF25,DR3,APO3,DDR3,TNFRSF12,WSL,WSL1
Species：Cynomolgus
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion：Gln 20 - Gly 203
Conjugate：Unconjugated
Molecular Weight：46.3 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 46.3 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
Purity：>90% as determined by SDS-PAGE.
Buffer：Tris with Glycine, Arginine and NaCl, pH7.5
