Background：Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family.
Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin.
Both MPF and the cleaved form of mesothelin are N-glycosylated.
Mesothelin / MSLN can interacts with MUC16.
The membrane-anchored forms of MSLN may play a role in cellular adhesion.
MPF potentiates megakaryocyte colony formation in vitro.
仕様
サイズ：25ug
Source：MABSol Biotinylated Human Mesothelin (296-580), Fc Tag (MSN-H826x) is expressed from human HEK293 cells. It contains AA Glu 296 - Gly 580 (Accession # AAH09272). It is the biotinylated form of Human Mesothelin (296-580), Fc Tag (MSN-H526x).
Molecule：Mesothelin
Synonyms：MSLN,Mesothelin,MPF
Species：Human
Tag：Fc Tag
Expression Systems：HEK293
Expression Rigeion：Glu 296 - Gly 580
Conjugate：UltraLys
Accession：AAH09272
Molecular Weight：59.1 kDa
Characteristics：This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 59.1 kDa. The protein migrates as 60-68 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level：Less than 1.0 EU per ug by the LAL method.
