特徴
- Background：cadherin 1(CDH1) Homo sapiens This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015],
仕様
- サイズ：100ul
- Source：Rabbit
- Applications：WB,IHC-p
- Species reactivity：Human
- Immunogen：Recombinant Protein of E-cadherin
- Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Observed band：125-130
- GeneID（Human）：CDH1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-7819-98
E-cadherin Polyclonal Antibody 100ul
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86-7822-86
E-cadherin Polyclonal Antibody 100ul
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86-7822-85
E-cadherin Polyclonal Antibody 100ul
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