特徴
- Background:collagen type XXV alpha 1 chain(COL25A1) Homo sapiens This gene encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC inhibits rather than facilitates amyloid fibril elongation (PMID: 16300410). A study of over-expression of this collagen in mice, however, found changes in pathology and behavior suggesting that the encoded protein may promote amyloid plaque formation (PMID: 19548013). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],
仕様
- サイズ:100ul
- Source:Rabbit
- Applications:WB,ELISA
- Species reactivity:Human,Mouse
- Immunogen:Synthetic peptide from human protein at AA range: 101-150
- Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:1 mg/ml
- Observed band:64
- GeneID(Human):COL25A1
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- アズワン株式会社 試薬・プロセス材料グループ
- TEL:06-6447-8641
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- E-mail:[email protected]
商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-7820-30
COL25A1 Polyclonal Antibody 100ul
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86-7820-55
COL25A1 Polyclonal Antibody 100ul
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掲載カタログ情報
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