特徴
- Background：Rho associated coiled-coil containing protein kinase 1(ROCK1) Homo sapiens This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18. [provided by RefSeq, Aug 2015],
仕様
- サイズ：100ul
- Source：Rabbit
- Applications：IF,WB,IHC-p,ELISA
- Species reactivity：Human,Mouse,Rat,Monkey
- Immunogen：The antiserum was produced against synthesized peptide derived from human Rock-1. AA range:262-311
- Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration：1 mg/ml
- Observed band：158
- GeneID（Human）：ROCK1
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- アズワン株式会社 試薬・プロセス材料グループ
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-7808-51
Rock-1 Polyclonal Antibody 100ul
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86-7809-37
Rock-1 Polyclonal Antibody 100ul
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