86-7807-76　［取扱停止］ZAP-70 Polyclonal Antibody 100ul　ES7535

特徴

• Background：zeta chain of T cell receptor associated protein kinase 70(ZAP70) Homo sapiens This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

仕様

• サイズ：100ul
• Source：Rabbit
• Applications：WB,IHC-p,ELISA
• Species reactivity：Human,Mouse
• Immunogen：The antiserum was produced against synthesized peptide derived from human ZAP-70. AA range:258-307
• Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration：1 mg/ml
• Observed band：70
• GeneID（Human）：ZAP70
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