Background:phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma(PIK3C2G) Homo sapiens The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
仕様
サイズ:100ul
Source:Rabbit
Applications:WB,ELISA
Species reactivity:Human
Immunogen:Synthesized peptide derived from the N-terminal region of human PI 3-Kinase C2γ.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.