86-7803-91　［取扱停止］Lck Polyclonal Antibody 100ul　ES6098

特徴

• Background：LCK proto-oncogene, Src family tyrosine kinase(LCK) Homo sapiens This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Aug 2016],

仕様

• サイズ：100ul
• Source：Rabbit
• Applications：WB,IF,ELISA
• Species reactivity：Human,Mouse,Rat
• Immunogen：The antiserum was produced against synthesized peptide derived from human Lck. AA range:460-509
• Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration：1 mg/ml
• Observed band：56
• GeneID（Human）：LCK
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