特徴
- Background:phosphoinositide kinase, FYVE-type zinc finger containing(PIKFYVE) Homo sapiens Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. Humans have multiple PtdIns proteins that differ by the degree and position of phosphorylation of the inositol ring. This gene encodes an enzyme (PIKfyve; also known as phosphatidylinositol-3-phosphate 5-kinase type III or PIPKIII) that phosphorylates the D-5 position in PtdIns and phosphatidylinositol-3-phosphate (PtdIns3P) to make PtdIns5P and PtdIns(3,5)biphosphate. The D-5 position also can be phosphorylated by type I PtdIns4P-5-kinases (PIP5Ks) that are encoded by distinct genes and preferentially phosphorylate D-4 phosphorylated PtdIns. In contrast, PIKfyve preferentially phosphorylates D-3 phosphorylated PtdIns. In addition to being a lipid kinase, PIKf
仕様
- サイズ:100ul
- Source:Rabbit
- Applications:IHC-p,ELISA
- Species reactivity:Human,Mouse,Rat
- Immunogen:The antiserum was produced against synthesized peptide derived from human PIP5K. AA range:273-322
- Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:1 mg/ml
- GeneID(Human):PIKFYVE
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
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86-7803-54
PIP5KIII Polyclonal Antibody 100ul
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86-7805-17
PIP5KIII Polyclonal Antibody 100ul
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