86-7801-97　SH-PTP2 Polyclonal Antibody 100ul　ES3439

特徴

• Background：protein tyrosine phosphatase, non-receptor type 11(PTPN11) Homo sapiens The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016],

仕様

• サイズ：100ul
• Source：Rabbit
• Applications：WB,IHC-p,ELISA
• Species reactivity：Human,Mouse,Rat
• Immunogen：The antiserum was produced against synthesized peptide derived from human SHP-2. AA range:546-595
• Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration：1 mg/ml
• Observed band：72
• GeneID（Human）：PTPN11
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