Background：function:May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.,induction:Upon B-cell activation.,PTM:Phosphorylated on tyrosine residues.,similarity:Contains 1 PH domain.,similarity:Contains 1 SH2 domain.,subcellular location:Membrane-associated after cell stimulation leading to its translocation.,subunit:Interacts with PtdIns(3,4,5)P3 and PLCG2. In vitro, interacts with PtdIns(3,4)P2.,tissue specificity:Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.,
仕様
サイズ：100ul
Source：Rabbit
Applications：WB,IHC-p,IF,ELISA
Species reactivity：Human,Mouse
Immunogen：The antiserum was produced against synthesized peptide derived from human DAPP1 around the phosphorylation site of Tyr139. AA range:105-154
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
