Background:DNA cross-link repair 1C(DCLRE1C) Homo sapiens This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
仕様
サイズ:100ul
Source:Rabbit
Applications:IHC-p,IF,ELISA
Species reactivity:Human
Immunogen:The antiserum was produced against synthesized peptide derived from human Artemis. AA range:482-531
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.