86-7796-97　IL-4Ra Polyclonal Antibody 100ul　ES2617

特徴

• Background：interleukin 4 receptor(IL4R) Homo sapiens This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012],

仕様

• サイズ：100ul
• Source：Rabbit
• Applications：WB,IF,ELISA
• Species reactivity：Human,Mouse
• Immunogen：The antiserum was produced against synthesized peptide derived from human IL-4R/CD124. AA range:463-512
• Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration：1 mg/ml
• Observed band：90
• GeneID（Human）：IL4R
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