86-7796-91　［取扱停止］Insulin R Polyclonal Antibody 100ul　ES5912

特徴

• Background：insulin receptor(INSR) Homo sapiens This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],

仕様

• サイズ：100ul
• Source：Rabbit
• Applications：IHC-p,IF,WB,ELISA
• Species reactivity：Human
• Immunogen：The antiserum was produced against synthesized peptide derived from human IR. AA range:1326-1375
• Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration：1 mg/ml
• Observed band：155
• GeneID（Human）：INSR
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