特徴
- Background：frizzled class receptor 6(FZD6) Homo sapiens This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.[provided by RefSeq, Aug 2011],
仕様
- サイズ：100ul
- Source：Rabbit
- Applications：WB,IF,ELISA
- Species reactivity：Human
- Immunogen：The antiserum was produced against synthesized peptide derived from human FZD6. AA range:121-170
- Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration：1 mg/ml
- Observed band：80
- GeneID（Human）：FZD6
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-7793-67
Frizzled-6 Polyclonal Antibody 100ul
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86-7793-66
Frizzled-6 Polyclonal Antibody 100ul
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