特徴
- Background：galanin receptor 2(GALR2) Homo sapiens Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simul
仕様
- サイズ：100ul
- Source：Rabbit
- Applications：WB
- Species reactivity：Human,Rat,Mouse
- Immunogen：Synthetic Peptide of GALR2
- Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
- Concentration：1 mg/ml
- Observed band：42
- GeneID（Human）：GALR2
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-7792-90
GALR2 Polyclonal Antibody 100ul
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86-7790-31
GALR2 Polyclonal Antibody 100ul
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