特徴
- Background：opioid receptor kappa 1(OPRK1) Homo sapiens This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Jan 2016],
仕様
- サイズ：100ul
- Source：Rabbit
- Applications：WB,ELISA
- Species reactivity：Human,Mouse,Rat,Monkey
- Immunogen：The antiserum was produced against synthesized peptide derived from human OPRK1. AA range:321-370
- Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration：1 mg/ml
- Observed band：48
- GeneID（Human）：OPRK1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-7787-02
KOR-1 Polyclonal Antibody 100ul
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86-7787-01
KOR-1 Polyclonal Antibody 100ul
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