Background:alternative products:Additional isoforms seem to exist,function:May participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double stranded DNA, and is capable of aggregating DNA. Also binds RNA.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subcellular location:Colocalizes with RAD51 to multiple nuclear foci.,subunit:Isoform 2 interacts with RAD51.,tissue specificity:Highly expressed in testis and thymus. Lower levels in colon and small intestine. Little or no expression in spleen, prostate, ovary and peripheral blood leukocytes.,
仕様
サイズ:100ul
Source:Rabbit
Applications:WB,ELISA
Species reactivity:Human,Mouse,
Immunogen:Synthesized peptide derived from human protein . at AA range: 90-170
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.