Background:disease:Patients with Raynaud disease produce antibodies that bind to RCC1.,function:Promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds to the chromatin. RCC1/Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA.,similarity:Contains 7 RCC1 repeats.,subcellular location:Becomes dispersed throughout the cytoplasm during mitosis.,
仕様
サイズ:100ul
Source:Rabbit
Applications:WB,IHC-p,ELISA
Species reactivity:Human,Mouse,Rat
Immunogen:Synthetic peptide from human protein at AA range: 301-350
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.