Background:LPS responsive beige-like anchor protein(LRBA) Homo sapiens The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012],
仕様
サイズ:100ul
Source:Rabbit
Applications:IHC-p
Species reactivity:Human,Mouse
Immunogen:Synthesized peptide derived from human protein . at AA range: 1970-2050
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.