Background:function:Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promotes FYN activation, possibly by disrupting intramolecular SH3-dependent interactions.,PTM:Phosphorylated on tyrosines by FYN (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the TOM1 family.,similarity:Contains 1 GAT domain.,similarity:Contains 1 VHS domain.,subunit:Interacts with FYN, GRB2 and PIK3R1 when phosphorylated.,
仕様
サイズ:100ul
Source:Rabbit
Applications:WB,ELISA
Species reactivity:Human,Rat,Mouse
Immunogen:Synthesized peptide derived from part region of human protein
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.