特徴
- Background:function:Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth. Binds to F-actin but not to RNA.,similarity:Belongs to the CYFIP family.,subcellular location:Highly expressed in the perinuclear region. Enriched in synaptosomes, membrane ruffles and at the tips of lamellipodia.,subunit:Interacts with the active GTP-bound form of RAC1. Interacts with FMR1/FMRP but does not bind to related proteins FXR1 or FXR2. Component of the WAVE2 complex composed of ABI1, CYFIP1/SRA1, NCKAP1/NAP1 and WASF2/WAVE2 (By similarity). Interacts through its C-terminus with the C-terminus of DPYSL2/CRMP2 which is necessary for DPYSL2-induced axon outgrowth.,
仕様
- サイズ:100ul
- Source:Rabbit
- Applications:WB,ELISA
- Species reactivity:Human
- Immunogen:Synthesized peptide derived from human protein . at AA range: 980-1060
- Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:1 mg/ml
- Observed band:137
- GeneID(Human):CYFIP1 KIAA0068
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-7765-31
CYFP1 Polyclonal Antibody 100ul
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86-7753-69
CYFP1 Polyclonal Antibody 100ul
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