特徴
- Background：cortactin(CTTN) Homo sapiens This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010],
仕様
- サイズ：100ul
- Source：Rabbit
- Applications：WB,IHC-p,ELISA
- Species reactivity：Human,Mouse,Rat
- Immunogen：The antiserum was produced against synthesized peptide derived from human Cortactin. AA range:388-437
- Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration：1 mg/ml
- Observed band：80
- GeneID（Human）：CTTN
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- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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86-7749-70
Cortactin Polyclonal Antibody 100ul
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86-7750-57
Cortactin Polyclonal Antibody 100ul
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86-7749-66
Cortactin Polyclonal Antibody 100ul
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86-7750-10
Cortactin Polyclonal Antibody 100ul
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