Background:CDC42 effector protein 5(CDC42EP5) Homo sapiens Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts [provided by RefSeq, Jul 2013],
仕様
サイズ:100ul
Source:Rabbit
Applications:WB,IHC-p,ELISA
Species reactivity:Human,Mouse
Immunogen:The antiserum was produced against synthesized peptide derived from human BORG3. AA range:1-50
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.