Background:kallikrein B1(KLKB1) Homo sapiens This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016],
仕様
サイズ:100ul
Source:Rabbit
Applications:WB,IHC-p,ELISA
Species reactivity:Human
Immunogen:The antiserum was produced against synthesized peptide derived from human KLKB1. AA range:341-390
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.