特徴
- Background：caveolin 1(CAV1) Homo sapiens The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010],
仕様
- サイズ：100ul
- Source：Rabbit
- Applications：WB,ELISA
- Species reactivity：Human,Mouse,Rat
- Immunogen：The antiserum was produced against synthesized peptide derived from human Caveolin-1. AA range:5-54
- Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration：1 mg/ml
- Observed band：25
- GeneID（Human）：CAV1
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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86-7742-48
Caveolin-1 Polyclonal Antibody 100ul
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86-7742-73
Caveolin-1 Polyclonal Antibody 100ul
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