Background：nuclear receptor corepressor 2(NCOR2) Homo sapiens This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011],
仕様
サイズ：100ul
Source：Rabbit
Applications：IHC-p,IF,WB,ELISA
Species reactivity：Human
Immunogen：The antiserum was produced against synthesized peptide derived from human NCOR2. AA range:511-560
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
