86-7738-21　PLC gamma1 Polyclonal Antibody 100ul　ES3235

特徴

• Background：phospholipase C gamma 1(PLCG1) Homo sapiens The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

仕様

• サイズ：100ul
• Source：Rabbit
• Applications：WB,IHC-p,ELISA
• Species reactivity：Human,Mouse,Rat,Monkey
• Immunogen：The antiserum was produced against synthesized peptide derived from human PLCG1. AA range:736-785
• Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration：1 mg/ml
• Observed band：150
• GeneID（Human）：PLCG1
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