86-7735-65　［取扱停止］CYP2D6 Polyclonal Antibody 100ul　ES2103

特徴

• Background：cytochrome P450 family 2 subfamily D member 6(CYP2D6) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 25% of commonly prescribed drugs. Its substrates include antidepressants, antipsychotics, analgesics and antitussives, beta adrenergic blocking agents, antiarrythmics and antiemetics. The gene is highly polymorphic in the human population; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. Some individuals with the poor metabolizer phenotype have no functional protein since they carry 2 null alleles whereas in other individuals the gene is absent. This gene can vary in

仕様

• サイズ：100ul
• Source：Rabbit
• Applications：WB,ELISA
• Species reactivity：Human
• Immunogen：Synthesized peptide derived from the Internal region of human CYP2D6.
• Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration：1 mg/ml
• Observed band：55
• GeneID（Human）：CYP2D6
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