Background:pyruvate kinase, muscle(PKM) Homo sapiens This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011],
仕様
サイズ:100ul
Source:Rabbit
Applications:IF,WB,IHC-p,ELISA
Species reactivity:Human,Mouse,Rat
Immunogen:The antiserum was produced against synthesized peptide derived from human PKM2. AA range:181-230
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.